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Deoksyniwalenol - czynnikiem wspomagającym bakteryjne martwicze zapalenia jelit u drobiu
Magdalena Gajęcka, Michał Dąbrowski, Łukasz Zielonka, Maciej Gajęcki

Zarówno Clostridium perfringens jak i mikotoksyny a wśród nich deoksyniwalenol (DON), indukują martwicze zapalenie jelit u drobiu i mają coraz większy wpływ na światową produkcję drobiarską (Antonissen i wsp., 2014). Patogeny oporne na antybiotyki oraz rosnące obawy obecności pozostałości chemicznych w mięsie drobiowym, w postaci antybiotyków, tradycyjnie stosowanych w celu zapobiegania i kontroli np. martwiczego zapalenia jelit u drobiu, są ograniczane lub zaczyna się myśleć o ich wycofaniu ze stosowania w produkcji drobiarskiej (Tian i wsp., 2016).
Z drugiej strony, trichoteceny zasadniczo występują w niskich stężeniach (Bryła i wsp., 2016), są one jednak trudne do wykrycia. Analiza pasz nie zawsze daje dokładną ocenę występujących w niej metabolitów grzybów pleśniowych. Spowodowane to jest faktem: (i) niedoskonałością procedur analitycznych; lub (ii) obecnością nowych, nieznanych jeszcze tego typu związków; oraz (iii) brakiem umiejętności rozpoznawania objawów klinicznych u zwierząt narażonych na obecność mikotoksyn w paszach, co nie pozwala na wykonanie odpowiednich/właściwych analiz diagnostycznych (Krska i wsp., 2008).
Celem przedstawionej pracy jest próba uzasadnienia wpływu jednego z czynników predysponujących, jakim jest DON, do rozwoju martwiczego zapalenia jelit.

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